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Table 3 ANCOVA model for primary endpoints and troponins adjusted for baseline tricuspid regurgitation, stage I surgical palliation, and cardiopulmonary bypass time

From: Autologous umbilical cord blood mononuclear cell therapy for hypoplastic left heart syndrome: a nonrandomized control trial of the efficacy and safety of intramyocardial injections

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Compared

Cardiac Function

n

Treatment group LS Means Estimate

(95% CI)

n

Control group

LS Means Estimate

(95% CI)

P value

Preop to 3 h postsurgery

Troponin T

36

0.790

(0.665, 0.915)

36

0.595

(0.470, 0.720)

0.037

Preop to 6 h postsurgery

Troponin T

39

0.700

(0.602, 0.798)

35

0.539

(0.436, 0.643)

0.032

Preop to 3 months

Apical FAC

39

-2.401

(-4.144, -0.658)

40

-2.444

(-4.164, -0.723)

0.972

Circumferential Strain

30

1.216

(-0.489, 2.922)

34

0.070

(-1.526, 1.667)

0.342

Longitudinal Strain

38

0.646

(-0.493, 1.786)

38

-1.555

(-2.695, -0.415)

0.009

Troponin T

13

0.417

(-1.154, 1.988)

14

0.425

(-1.075, 1.926)

0.994

Preop to 12 months

Apical FAC

33

-3.792

(-5.589, -1.994)

31

-4.598

(-6.454, -2.743)

0.536

 

Circumferential Strain

24

0.957

(-1.037, 2.953)

19

1.887

(-0.372, 4.147)

0.548

 

Longitudinal Strain

31

0.489

(-0.737, 1.715)

31

-0.495

(-1.722, 0.731)

0.263

 

Troponin T

13

-0.024

(-0.025, -0.023)

11

-0.025

(-0.026, -0.024)

0.147

  1. ANCOVA: analysis of covariance; FAC: fractional area change